Trials

[Jo Bowyer]

How one NHS anaesthetist is fighting international medical research fraud

https://theconversation.com/how-one-...search%20fraud

Carlisle’s method does not definitely say whether a trial report is fraudulent. It’s a screening method that suggests that some trial reports need to be examined more thoroughly to check whether anything untoward is going on. There could, sometimes, be innocent explanations for the unusual patterns of data that the method detects.

[Jo Bowyer]

Community-based football in men with prostate cancer: 1-year follow-up on a pragmatic, multicentre randomised controlled trial

https://journals.plos.org/plosmedici...l.pmed.1002936

This ticks so many boxes!

[Jo Bowyer]

Brain mechanisms have potential to block arthritis pain

Existing compound produces pain-relieving effects and relieves anxiety

https://www.sciencedaily.com/release...1010075415.htm

[Jo Bowyer]

Humans have salamander-like ability to regrow cartilage in joints

The process could be harnessed as a treatment for osteoarthritis

https://www.sciencedaily.com/release...1009142852.htm

[Jo Bowyer]

Recovering the capability to work among patients with chronic low Back pain after a four-week, multidisciplinary biopsychosocial rehabilitation program: 18-month follow-up study

https://bmcmusculoskeletdisord.biome...891-019-2831-6

[Jo Bowyer]

The efficacy and safety of continuous versus single-injection popliteal sciatic nerve block in outpatient foot and ankle surgery: a systematic review and meta-analysis

https://bmcmusculoskeletdisord.biome...891-019-2822-7

[Jo Bowyer]

Effects of eccentric exercise in patients with subacromial impingement syndrome: a systematic review and meta-analysis

https://bmcmusculoskeletdisord.biome...891-019-2796-5

Evidence of low certainty suggests that eccentric exercise may provide a small but likely not clinically important reduction in pain compared with other types of exercise in patients with subacromial impingement syndrome. It is uncertain whether eccentric exercise improves function more than other types of exercise (very low certainty of evidence). Methodological limitations of existing studies make these findings susceptible to change in the future.

[Jo Bowyer]

Cervical proprioception and its relationship with neck pain intensity in subjects with cervical spondylosis

https://bmcmusculoskeletdisord.biome...891-019-2846-z

To date, to our knowledge, this is the first study of its kind that has evaluated and shown a significant positive correlation between neck pain intensity and position sense in subjects with CS. Pain models that were experimentally induced showed a positive influence between pain and proprioception [31]. The substances that are chemically mediated during the pain response might alter free nerve ending discharges due to sensitization and produce abnormal pain afferents (gamma-motor neuron and muscle spindle), thus impairing kinesthetic input [32]. Contrary to our study, Lee et al.’s study did not show any association between neck pain intensity and cervical proprioceptive sense in chronic neck pain subjects; rather, they noted that a higher pain frequency was positively associated with increased JPEs [6]. Our study results cannot be compared with et al. study as the sample characteristics and cervical proprioception testing methodological considerations are different from the current study. Further studies are required to see the association between neck pain frequency, duration, and intensity and proprioception in a larger sample of CS subjects.