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HPA Axis, Stress, and Chronic Pain

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  • ??? HPA Axis, Stress, and Chronic Pain

    This is a question and request for information:
    Does anyone have good resources or articles about the HPA Axis especially as it relates to chronic stress and chronic pain?

    Any other thoughts on this topic would also be appreciated! It is one area that I know very little about, and I'd love to learn more.
    Thank you.

  • #2
    Translational Pain Research: From Mouse to Man

    https://www.somasimple.com/forums/fo...m-mouse-to-man

    Hypothalamic-pituitary-adrenal axis feedback sensitivity in different states of back pain

    https://www.sciencedirect.com/scienc...06453018308138

    Highlights

    Relationship of pain chronicity, stress regulation, comorbidity and somatosensation. Hyper-suppression of cortisol following dexamethasone in subacute back pain. Negative association of cortisol with pain intensity and anxiety in subacute pain. Proposed stress model of individual vulnerability in the chronic pain transition.
    Jo Bowyer
    Chartered Physiotherapist Registered Osteopath.
    "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

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  • #3
    Thanks Jo!

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