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Causal pathway for osteoarthrosis of the knee

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  • Young athletes who require ACL reconstruction may benefit from additional procedure

    Multi-center clinical trial shows LET procedure can improve patient outcomes

    https://www.sciencedaily.com/release...0521124544.htm
    Jo Bowyer
    Chartered Physiotherapist Registered Osteopath.
    "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

    Comment


    • Accelerated knee osteoarthritis is associated with pre-radiographic degeneration of the extensor mechanism and cruciate ligaments: data from the Osteoarthritis Initiative

      https://bmcmusculoskeletdisord.biome...891-019-2685-y
      Jo Bowyer
      Chartered Physiotherapist Registered Osteopath.
      "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

      Comment


      • Response to the blog ‘Brain-targeted treatment in people with painful knee osteoarthritis in tertiary care: was it feasible?

        https://bodyinmind.org/response-brai...ody+in+Mind%29
        Jo Bowyer
        Chartered Physiotherapist Registered Osteopath.
        "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

        Comment


        • Physiotherapist as primary assessor for patients with suspected knee osteoarthritis in primary care—a randomised controlled pragmatic study

          https://bmcmusculoskeletdisord.biome...891-019-2690-1

          There were no differences in HrQoL, when adjusted for pain and physical function, for patients with KOA when the healthcare process was initiated with physiotherapist assessment compared to physician assessment in primary care. Both assessments resulted in significantly higher HrQoL at the 12-month follow-up. The results imply that physiotherapists and physicians in primary care are equally qualified as primary assessors.
          Jo Bowyer
          Chartered Physiotherapist Registered Osteopath.
          "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

          Comment


          • Kneeling ability after total knee replacement

            https://online.boneandjoint.org.uk/d...-5241.4.180085

            The primary reasons that patients elect to undergo total knee replacement (TKR) are to gain improvements in pain and walking ability.1 However, patients often have high expectations of the outcome of their TKR and want more from their operation than pain relief and improvement in basic mobility.2 This includes a return to important higher function activities, such as kneeling.13 The majority of patients expect to be able to kneel after TKR,2,4,5 however, these expectations are frequently not met,1,6 with between 50% and 80% of patients reporting that they have difficulty kneeling or do not kneel in the months and years after TKR.7
            Jo Bowyer
            Chartered Physiotherapist Registered Osteopath.
            "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

            Comment


            • Varus thrust visualized during gait was associated with inverted foot in patients with knee osteoarthritis: An exploratory study

              https://www.sciencedirect.com/scienc...328?via%3Dihub
              Jo Bowyer
              Chartered Physiotherapist Registered Osteopath.
              "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

              Comment


              • Impact of exercise on articular cartilage in people at risk of, or with established, knee osteoarthritis: a systematic review of randomised controlled trials

                https://bjsm.bmj.com/content/53/15/940.full

                Therapeutic exercise is a first-line treatment in OA: it is safe11 and effectively reduces pain and improves function.12–14 Less is known about the effects from therapeutic exercise on knee joint articular cartilage. However, exercise at higher doses, such as playing sports at elite level, is associated with development of OA, suggesting injury and also load in itself as being a contributing factor.15 16 The mechanical loading generated from exercise, in combination with cell biology, and in some cases inflammatory factors, may alter the function of articular cartilage.17 While there are no conclusive studies, it has been suggested that exercise may prevent or delay OA onset.18 In support of this, two cohort studies found that a moderate dose of physical activity could slow down cartilage degeneration in middle-aged individuals at early OA stages.19 20 Furthermore, initiating an accelerated and progressive weight-bearing intervention a few hours after cartilage surgery was shown to be safe for the cartilage and resulted in more favourable clinical outcomes compared with a delayed knee joint loading exercise intervention.21 Also, in patients having had meniscectomy, therapeutic exercise increased cartilage glycosaminoglycan (GAG) content.22 However, patients at risk of, or with, knee OA still often believe that exercise may wear down their knee joints, creating a barrier to exercise.23
                Jo Bowyer
                Chartered Physiotherapist Registered Osteopath.
                "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                Comment


                • The global state of research in nonsurgical treatment of knee osteoarthritis: a bibliometric and visualized study

                  https://bmcmusculoskeletdisord.biome...891-019-2804-9
                  Jo Bowyer
                  Chartered Physiotherapist Registered Osteopath.
                  "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                  Comment


                  • Wear & Repair: an Osteoarthritis knee story using healthy linguistics

                    https://noijam.com/2019/09/11/wear-r...y-linguistics/
                    Jo Bowyer
                    Chartered Physiotherapist Registered Osteopath.
                    "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                    Comment


                    • The association between pain catastrophizing, physical function and pain in a cohort of patients undergoing knee arthroplasty

                      https://bmcmusculoskeletdisord.biome...891-019-2787-6
                      Jo Bowyer
                      Chartered Physiotherapist Registered Osteopath.
                      "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                      Comment


                      • The effect of mobilization with movement on pain and function in patients with knee osteoarthritis: a randomized double-blind controlled trial

                        https://bmcmusculoskeletdisord.biome...891-019-2841-4

                        Jo Bowyer
                        Chartered Physiotherapist Registered Osteopath.
                        "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                        Comment


                        • Relative difference among 27 functional measures in patients with knee osteoarthritis: an exploratory cross-sectional case-control study

                          https://bmcmusculoskeletdisord.biome...891-019-2845-0
                          Jo Bowyer
                          Chartered Physiotherapist Registered Osteopath.
                          "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                          Comment


                          • Association between thigh muscle strength four years after partial meniscectomy and radiographic features of osteoarthritis 11 years later

                            https://bmcmusculoskeletdisord.biome...891-019-2875-7

                            The menisci have important shock absorbing and load transmitting functions and contribute also to joint stability [1,2,3]. In middle-aged or elderly subjects it is common that meniscal tears occurs after a minor trauma as the meniscus is undergoing degenerative processes [4, 5]. Meniscal tear is a well-known risk factor for knee osteoarthritis (OA) [4], and according to previous studies about half of meniscus surgery patients develop radiographic OA 10–20 years after meniscectomy [5,6,7,8].

                            In the general population thigh muscle weakness has been suggested to be an independent risk factor for developing symptomatic or radiographic knee OA in both men and women [9, 10], and quadriceps weakness has been reported up to 5 years after arthroscopic partial meniscectomy (APM) [11,12,13,14]. However, the independent effect of thigh muscle weakness on knee OA after meniscectomy has not been elucidated. Weak thigh muscles may expose the articular cartilage to harmful loading since dynamic stability as well as shock absorbing function of the muscles are impaired [15, 16]. After meniscal injury and surgery, joint biomechanics may be altered which puts additional stress on the cartilage [17, 18]. Identifying the relative importance of modifiable factors associated with knee OA development after meniscectomy could help improve strategies for prevention of knee OA.
                            ​​​​​​​
                            Jo Bowyer
                            Chartered Physiotherapist Registered Osteopath.
                            "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                            Comment


                            • Substantive molecular and histological changes within the meniscus with tears

                              https://bmcmusculoskeletdisord.biome...891-019-2943-z

                              Our findings suggest that the torn meniscus, particularly when combined with a torn ACL, has an intrinsic tendency to get degraded at the molecular level. Additionally, miR-381-3p, miR-455-3p, miR-193b-3p, and miR-92a-3p may contribute to the progression of meniscus degeneration, which might act as potential biomarkers for subsequent development of OA. Finally, our clinical results show that patients with a combined injury pattern may have relatively worse joint function.
                              Jo Bowyer
                              Chartered Physiotherapist Registered Osteopath.
                              "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                              Comment

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