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Papers related to ageing

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  • Jo Bowyer
    replied
    After 40 years, the Alzheimer’s Association sees signs of progress against a devastating disease. Is it real?
    https://www.statnews.com/2020/02/24/...f9e1-151138121

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  • Jo Bowyer
    replied
    Neighborhood features and one's genetic makeup interact to affect cognitive function

    https://www.sciencedaily.com/release...0219092534.htm

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  • Jo Bowyer
    replied
    Why hasn’t evolution dealt with the inefficiency of ageing?

    https://aeon.co/ideas/why-hasnt-evol...1f787-69418129

    Ultimately, reproduction is the focal point by which evolution acts. Human evolution permits late-onset effects on health that arise after this reproduction window, especially if it benefits individuals in their early life exploits. In the context of environmental constraints, the individual must effectively allocate resources, creating trade-offs between reproduction, safety and long-term health. In the drive towards the cure for ageing, evolutionary medicine has the potential to further our understanding of why human diseases arise, and elucidate the unanticipated costs of subverting this intrinsic biological process.


    One of my favourite specialities within my practice as a generalist is care of the elderly. I am, as I write, entering early old age and I have parents in late old age, both have cognitive impairment which my brothers and I address by keeping them active and engaged. As for me, ageing feels like trying to run up a downgoing escalator. Work, and keeping up to date with emerging evidence helps, as does good diet and optimal BMI, but it's tough. I have a colleague who works in the same building who is 10 years ahead of me, the receptionists worry about him as he is often fully booked and looks exhausted when he has reached the end of his list.

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  • Jo Bowyer
    replied
    Alzheimer 'tau' protein far surpasses amyloid in predicting toll on brain tissue

    https://www.sciencedaily.com/release...0101144012.htm

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  • Jo Bowyer
    replied
    Why ageing should be classified as a disease

    https://theconversation.com/why-agei...%20a%20disease

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  • Jo Bowyer
    replied
    Home care as reablement or enabling arrangements? An exploration of the precarious dependencies in living with functional decline

    https://onlinelibrary.wiley.com/doi/...mpaign=woletoc

    This approach to care, we argue, would have several practical as well as ethical implications. First, in terms of how older people are perceived, it considers the need to recognise their often prolonged, conscientious and creative efforts to establish and attune socio‐material arrangements enabling them to stave off public home care. Society therefore needs to recognise that older people's reluctance to participate in reablement is not simply down to a lack of motivation, but often caused by a genuine lack of physical capacities. Missing this point involves the risk of failing to meet the needs of older people.

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  • Jo Bowyer
    replied
    As we age, oral health plays increasing role in overall health

    All health care professionals need to promote good oral hygiene in the elderly population

    https://www.sciencedaily.com/release...0926114004.htm

    Periodontitis is associated with a variety of medical conditions including cardiovascular disease and diabetes. Patients with replacement heart valves and prosthetic joints should be particularly careful regarding their oral hygiene, according to the authors.

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  • Jo Bowyer
    replied
    For the first time walking patterns identify specific types of dementia

    https://www.sciencedaily.com/release...0919211806.htm

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  • Jo Bowyer
    replied
    The influence of ageing on the incidence and site of trauma femoral fractures: a cross-sectional analysis

    https://bmcmusculoskeletdisord.biome...891-019-2803-x

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  • Jo Bowyer
    replied
    Neuroinflammation and Functional Connectivity in Alzheimer's Disease: Interactive Influences on Cognitive Performance

    https://www.jneurosci.org/content/39....abstract?etoc

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  • Jo Bowyer
    replied
    Diet's effect on gut bacteria could play role in reducing Alzheimer's risk

    https://www.sciencedaily.com/release...0903120514.htm

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  • Jo Bowyer
    replied
    Alzheimer's disease destroys neurons that keep us awake

    Study suggests Tau tangles, not amyloid plaques, drive daytime napping that precedes dementia

    https://www.sciencedaily.com/release...0812075523.htm

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  • Jo Bowyer
    replied
    How development of the ‘self’ in infants provides clues to the breakdown of memory in dementia

    https://theconversation.com/how-deve...0in%20dementia

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  • Jo Bowyer
    replied
    Common mechanisms involved in Alzheimer's disease and type 2 diabetes: a key role of chronic bacterial infection and inflammation

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925815/

    Increasing evidence supports an association between periodontal and systemic disorders [33, 34].
    Possibly the most significant paper I have posted from the viewpoint of a generalist physiotherapist. Oral health is key to healthy ageing.

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  • Jo Bowyer
    replied
    Positive attitudes about aging may pay off in better health

    https://www.sciencenews.org/article/...orspicks080419

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