Announcement

Collapse
No announcement yet.

Papers related to ageing

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • Social isolation, cognitive reserve, and cognition in healthy older people

    http://journals.plos.org/plosone/art...l.pone.0201008


    Cognitive health is an important aspect of healthy ageing. As people get older, they may experience subtle changes in their cognitive ability, a process referred to as ‘cognitive ageing’ [1]. It is widely thought that while cognitive ageing is a normal part of healthy ageing, more significant changes in cognition are not [2, 3]. Variation is observed in the trajectories of cognitive ageing across older people [4]. While some individuals retain a high level of cognitive ability from mid- to late- life, others may experience decline [5]. A decline in cognitive function can be detrimental to the independence, wellbeing, and quality of life of older people [6, 7]. Understanding the mechanisms underlying differences in cognitive ageing is important to reduce the impact of poor cognitive function in later life.

    Cognitive reserve is a theoretical concept that can account for the differences observed in late-life cognitive trajectories. The theory suggests that individuals differ in their degree of resilience against age-related brain pathology and hence may show differences in cognitive function in relation to an equivalent level of pathology [8, 9]. These differences are linked to the ability of an individual to recruit protective mechanisms associated with cognitive abilities built up over the lifespan, and actively compensate for damage caused by pathology [10]. Observational and some experimental evidence suggests that reserve can be built up through a combination of experiences across the lifespan, such as physical exercise, education, occupation, and participation in social and cognitively stimulating activities. These experiences may create a buffer against cognitive decline by enhancing brain processes such as neural connectivity and hence cognitive ability. This might then protect the individual against the effects of disease pathology in the first instance, and also compensate for damage and recruit alternative neural pathways when required. This may reduce or delay the extent of impairment experienced and protect against the expression of pathological processes [11].

    Compared to other lifestyle factors that may build cognitive reserve, the association between social connections and cognition is less well understood.
    Jo Bowyer
    Chartered Physiotherapist Registered Osteopath.
    "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

    Comment


    • Why some people with brain markers of Alzheimer's have no dementia

      https://www.sciencedaily.com/release...0817093810.htm
      Jo Bowyer
      Chartered Physiotherapist Registered Osteopath.
      "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

      Comment


      • Resistance training and exercise-motivation go hand-in-hand

        https://www.sciencedaily.com/release...0816101937.htm
        Jo Bowyer
        Chartered Physiotherapist Registered Osteopath.
        "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

        Comment


        • Open reduction internal fixation vs non-operative management in proximal humerus fractures: a prospective, randomized controlled trial protocol

          https://bmcmusculoskeletdisord.biome...891-018-2223-3
          Jo Bowyer
          Chartered Physiotherapist Registered Osteopath.
          "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

          Comment


          • Age shouldn’t be a barrier to playing competitive sports

            https://theconversation.com/age-shou...itive%20sports
            Jo Bowyer
            Chartered Physiotherapist Registered Osteopath.
            "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

            Comment


            • Impact of osteoporosis on the risk of dementia in almost 60,000 patients

              https://www.sciencedaily.com/release...0820150144.htm


              Osteoporosis is estimated to affect 200 million women across the world. In Germany, the prevalence of this chronic disease among people aged 50 years and older is around 15%. In recent decades, several authors have analyzed the impact of osteoporosis on the risk of cognitive decline, but, most of these studies have been conducted outside Europe. The goal of the present study was to investigate the impact of osteoporosis on the risk of developing dementia in almost 60,000 patients followed for up to 20 years in more than 1,200 general practices in Germany.
              Jo Bowyer
              Chartered Physiotherapist Registered Osteopath.
              "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

              Comment


              • Aging and the intricacies of the immune system

                http://blogs.biomedcentral.com/on-bi...immune-system/

                Thanks to improvements in healthcare, nutrition and lifestyle conditions, lifespan has doubled over the course of a couple of centuries. A baby girl born in 1841 could expect to live to 42: a baby girl born in 2016 can expect to live to 83. People are living longer and older people are healthier than they ever were.

                Nevertheless, gains in healthspan have not kept pace with lifespan. An aging population presents major economic, health and social challenges.
                Jo Bowyer
                Chartered Physiotherapist Registered Osteopath.
                "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                Comment


                • Dietary Fiber Reduces Brain Inflammation During Aging

                  https://neurosciencenews.com/fiber-a...ammation-9865/

                  Jo Bowyer
                  Chartered Physiotherapist Registered Osteopath.
                  "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                  Comment


                  • The relationship of self-efficacy to catastrophizing and depressive symptoms in community-dwelling older adults with chronic pain: A moderated mediation model

                    https://journals.plos.org/plosone/ar...l.pone.0203964
                    Jo Bowyer
                    Chartered Physiotherapist Registered Osteopath.
                    "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                    Comment


                    • One-legged stance sway of older adults with and without falls

                      https://journals.plos.org/plosone/ar...l.pone.0203887


                      Postural instability is a common problem among older people, and it is associated with mobility impairments, activity limitation and fear of falling. The evaluation of postural control can contribute to the early detection of balance deficits and help health professionals to manage this problem to prevent falls in older adults. The aim of this study was to identify center of pressure cut-offs to differentiate between older adults with and without falls in the past 12 months. The participants were 170 older adults (mean age 67 years, 50 fallers and 120 non-fallers). Center of pressure area and sway velocity in the anterior-posterior and medio-lateral directions were assessed using a force platform during three 30s one-legged stance trials with eyes open. The mean across trials was used for analysis. The time-limit (how long the participant was able to stay in one-legged stance, up to 30s) was also assessed. Fallers had poorer postural control than non-fallers (effect size ≥ 0.52, P <0.05). The cut-offs identified were 10.3 cm2 for Center of pressure area, 2.9 cm/s for velocity in the anterior-posterior, and 3.4 cm/s for medio-lateral velocity. The force platform parameters obtained an area under the curve of 0.72, with sensitivity of 78% and specificity of 68%. There were no significant differences between non-fallers and fallers for time-limit variable (17 seconds vs. 18 seconds). Force platform parameters during one-legged stance were associated with history of falls in older adults. The cut-offs obtained acceptable area under curve, sensitivity and specificity, with center of pressure area presenting the best performance to differentiate between fallers and non-fallers.
                      Jo Bowyer
                      Chartered Physiotherapist Registered Osteopath.
                      "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                      Comment


                      • Zombie Cells Found in Mouse Brains Prior To Cognitive Loss

                        https://neurosciencenews.com/cogniti...ie-cells-9892/

                        “Senescent cells are known to accumulate with advancing natural age and at sites related to diseases of aging, including osteoarthritis; atherosclerosis; and neurodegenerative diseases, such as Alzheimer’s and Parkinson’s,” says Darren Baker, Ph.D., a Mayo Clinic molecular biologist and senior author of the paper. “In prior studies, we have found that elimination of senescent cells from naturally aged mice extends their healthy life span.”
                        Jo Bowyer
                        Chartered Physiotherapist Registered Osteopath.
                        "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                        Comment


                        • Poor coherence in older people's speech is explained by impaired semantic and executive processes

                          https://elifesciences.org/articles/3...18-elife-alert

                          During a conversation, each person must plan and monitor what they say to make sure it is relevant to the discussion. This is called maintaining coherence during speech. Studies suggest that as people get older they find it harder to remain coherent, and become more likely to produce irrelevant or off-topic information when speaking. This reduces how effectively they communicate and can have negative effects on their social interactions. However, little is known about how thinking skills affect coherence in speech and why this declines in later life.
                          It's a nightmare when trying to get a history, having family members in can help.
                          Jo Bowyer
                          Chartered Physiotherapist Registered Osteopath.
                          "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                          Comment


                          • Periodontal Disease Bacteria May Kick Start Alzheimer’s

                            https://neurosciencenews.com/periodo...zheimers-9955/
                            Jo Bowyer
                            Chartered Physiotherapist Registered Osteopath.
                            "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                            Comment


                          • Aging and Decision Making: Who Makes Riskier Decisions?

                            https://neurosciencenews.com/aging-d...n-making-9970/

                            Brain imaging research has found that subjective value is represented similarly in the medial prefrontal cortex (MPFC) across all ages. Despite this common network, Seaman and her colleagues have found significant differences in decision-making in older individuals.

                            The first difference comes in the form of reward. Older individuals are likely to be more invested in the outcome of a task if the reward is social or health-related rather than monetary. Consequently, they are more likely to want these health and social rewards sooner and with higher certainty than younger individuals are. Understanding the salience of these rewards is crucial to designing future experiments to identify decision-making differences in older adults.
                            Jo Bowyer
                            Chartered Physiotherapist Registered Osteopath.
                            "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                            Comment


                            • Association between sarcopenia and low back pain in local residents prospective cohort study from the GAINA study

                              https://bmcmusculoskeletdisord.biome...891-017-1807-7
                              Jo Bowyer
                              Chartered Physiotherapist Registered Osteopath.
                              "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                              Comment

                              Working...
                              X