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  • Taking CRISPR from clipping scissors to word processor

    New platform transforms gene editor into precision tool

    https://www.sciencedaily.com/release...0508102209.htm
    Jo Bowyer
    Chartered Physiotherapist Registered Osteopath.
    "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

    Comment


    • The world's tiniest first responders

      https://www.sciencedaily.com/release...0620170951.htm
      Jo Bowyer
      Chartered Physiotherapist Registered Osteopath.
      "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

      Comment


      • Finding the proteins that unpack DNA

        https://www.sciencedaily.com/release...0712114557.htm
        Jo Bowyer
        Chartered Physiotherapist Registered Osteopath.
        "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

        Comment


        • How do muscles know what time it is?

          https://www.sciencedaily.com/release...0821111938.htm

          Circadian clocks are present in all cells of the body, and have a pervasive influence on all aspects of human physiology. This is because they regulate homeostasis by anticipating rhythmic changes in behavior and nutritional state, and by compartmentalizing incompatible metabolic pathways within precise temporal windows.
          Jo Bowyer
          Chartered Physiotherapist Registered Osteopath.
          "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

          Comment


          • The Link Between Obesity, Genetics and the Brain

            https://neurosciencenews.com/genetic...ty-brain-9762/
            Jo Bowyer
            Chartered Physiotherapist Registered Osteopath.
            "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

            Comment


            • What Time is it in Your Body?

              https://neurosciencenews.com/body-in...ck-blood-9842/

              Processes in nearly every tissue and organ system in the body are orchestrated by an internal biological clock, which directs circadian rhythm, such as the sleep-wake cycle. Some individuals’ internal clocks are in sync with external time but others are out of sync and considered misaligned.
              “This is really an integral part of personalized medicine,” said coauthor Dr. Phyllis Zee, chief of sleep medicine in neurology at Feinberg and a Northwestern Medicine neurologist. “So many drugs have optimal times for dosing. Knowing what time it is in your body is critical to getting the most effective benefits. The best time for you to take the blood pressure drug or the chemotherapy or radiation may be different from somebody else.”
              The test measures 40 different gene expression markers in the blood and can be taken any time of day, regardless of whether the patient had a good night’s sleep or was up all night with a baby. It is based on an algorithm developed by Braun and colleagues by drawing subjects’ blood every two hours and examining which genes were higher or lower at certain times of day. Scientists also used gene expression data from studies conducted at four other centers.
              Jo Bowyer
              Chartered Physiotherapist Registered Osteopath.
              "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

              Comment


              • High-resolution genomic map gives scientists unprecedented view of brain development

                https://www.sciencedaily.com/release...0913142033.htm

                Summary:
                Researchers have created a massive database of the changes in gene activity of individual cells in the cerebellum during embryonic development and immediately after birth. The analysis of thousands of brain cells isolated from mice offers researchers a high-resolution map that enables scientists to view the detailed genomic changes cells undergo as the cerebellum wires its neural circuitry.
                Jo Bowyer
                Chartered Physiotherapist Registered Osteopath.
                "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                Comment


                • Mathematics meets biology to uncover unexpected biorhythms

                  https://www.sciencedaily.com/release...0920115521.htm

                  "Circadian rhythms are physical, mental and behavioral changes that follow a 24-hour cycle driven by environmental light and darkness. One of the best known circadian cycles is sleeping at night and being awake during the day," said corresponding author Dr. Clifford C. Dacso, professor of molecular and cellular biology and member of the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine. "These biological rhythms reflect complex interactions at the molecular level that occur among the paths mediating the expression of genes into active proteins carrying functions in the cell."

                  There is evidence, however, that other biological cycles exist in addition to 24-hour rhythms. Blood pressure, body temperature, cognitive performance, some circulating hormones, reaction to stress and responses to drug therapy, for instance, appear to follow a 12-hour rhythm, but little is known about the biological basis of it. Dacso and his colleagues set out to find out answers.
                  Jo Bowyer
                  Chartered Physiotherapist Registered Osteopath.
                  "Out beyond ideas of wrongdoing and rightdoing,there is a field. I'll meet you there." Rumi

                  Comment

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